Important Notes
Important Notes – Resident Evil 4
This section covers critical information every player should know before diving into Resident Evil 4 (both the 2005 original and the 2023 remake). Read carefully to avoid irreversible mistakes, wasted resources, and frustrating surprises.
---
⚠️ Irreversible Choices & Missable Content
- Blue Medallions (Remake & Original): Destroying all 15 Blue Medallions in each chapter rewards a unique weapon (e.g., the Punisher in Chapter 2). If you miss even one, you cannot return to that area after progressing past a certain point. In the remake, Chapter 7 and later areas become permanently inaccessible. Save before searching; use a guide.
- Repeated Passes of Areas (Original): Areas like the Village, Castle, and Island are strictly sequential. Once you leave, you cannot return. Missed treasures, keys, or side quests are gone forever.
- Costume Keys (Remake): The "Jacket" and "Sunglasses" unlock for Leon require not interacting with certain merchants or completing specific tasks in a single playthrough. If you sell a required treasure or skip a Request, you cannot unlock them until New Game+.
- Ashley's Armor (Remake): Unlocking the Ashley armor requires completing the game once, then on a New Game+ run, completing the game again with the original save. It's a two-playthrough commitment. Missing the first playthrough file means you cannot unlock it.
- Village Chief's Key (Original): The key to the chief's house is missable if you do not pick it up before the cabin siege. After that, you can't go back.
###