All Game Items

Resident Evil 2 (2019) – All Game Items Guide



This guide catalogs every significant item in Resident Evil 2 (2019), grouped by category. Descriptions cover purpose, acquisition, optimal use, and any upgrades or synergy.

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Weapons



Weapons are your primary means of defense. Most can be upgraded with parts found throughout RPD and the sewers.

WeaponAmmoAcquisitionNotes
Matilda (9mm Handgun)9mmLeon’s starting weapon.Standard semi-auto. Upgrade with: High-Capacity Magazine (RPD East Office safe 9►15►7) – 24 rounds; Silencer (Boiler Room in Sewers – narrow room) – stealth headshots; Red Dot Sight (Sewers, near orphic puzzle) – improved accuracy.
W-870 (Shotgun)Shotgun ShellsLeon: RPD West office lockers (use bolt cutters). Claire: S.T.A.R.S. office at RPD (after getting club key).Pump-action. Upgrade with Stock (RPD – after statue moves from library) – faster fire rate & reload. Best used on lickers or multiple enemies.
GM 79 (Grenade Launcher)Flame, Acid, Explosive RoundsFloor 3 of RPD (find in locked cabinet in the library/study, requires the hidden ladder).Claire only. Explosive rounds for boss fights, flame rounds for IVy zombies.
Lightning Hawk (Magnum)Magnum RoundsParking Garage – inside a locked container (use diamond key from RPD safe). Also in sewer’s weapons locker.Extremely powerful; save for bosses or tough enemies (lickers, G-adults). Ammo scarce.
JMB Hp (Handgun)9mmClaire’s starting weapon.Same upgrade options as Matilda (magazine, suppressor, red dot).
Sparkshot (High Voltage)High Voltage CartridgesRPD 2F waiting room (inset into a panel – uses crank wheel to open).Stuns enemies temporarily, consumes rare cartridges. Good for saving resources.
FlamethrowerFuel (found in red canisters)Sewers – in the maze-like section near the “control room” after the piston puzzle.Only available to both characters. Devastating against bugs, ivy zombies, and organic bosses. Fuel can be mixed from large canisters? Actually, you find full canisters.
Rocket Launcher (AT4)One-shotReward for completing Scenario A (both characters). Appears in item box at start of Scenario B.One-hit kills on most bosses. Use on final boss (Super Tyrant) for instant stage completion.
GrenadeFound in many crates and from certain enemies (zombies drop occasionally).Standard throwable. Stuns groups, kills weak enemies. Can be combined with flash to blind + damage? Only standalone use.
Flash GrenadeFound near stairwells, lockers.Blinds all enemies in radius, stuns lickers, destroys Mr. Raccoon collectible if thrown? No, only temporarily disables them.
Combat KnifeInfinite durability (secret) – Reward for finishing game on hardcore with S+ rank. Standard one breaks after a few uses.Default melee. Stun enemies, break crates. Replaceable – many found.
Hand GrenadeSame as grenade – different naming? In RE2 they are “Grenade” only.
#### Weapon Upgrades

  • Weapon Stock – Faster fire rate and reload for shotgun.

  • High‑Capacity Magazine – Increases ammo capacity for handguns.

  • Red Dot Sight – Tightens crosshair for better accuracy.

  • Suppressor – Quiet shots prevent attracting nearby enemies.

  • Extended Magazine for Matilda – Actually the high-cap is the only one.


Synergy: Pair suppressor with handgun for stealth kill chains; use grenade launcher flame rounds on ivy zombies before using shotgun. Flash grenade + knife combo for crowd control.

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Consumables



ItemEffectNotes
Green HerbHeals a small amount of health.Combine with Green Herb for Green+Green (better) or Blue (temporary defense) or Red (full heal).
Blue HerbCures poison or provides defense.Combine with Green for Green+Blue (heal + poison cure).
Red HerbBoosts healing when combined with Green (Green+Red = full heal).Rare – found in labs and sewers.
Mixed Herb (any variant)See above.
First Aid SprayFully restores health (from Danger to Fine).One use; can be used on partner in co-op? Not in this game.
Hand GrenadeExplosive; kills weak zombies, stuns bosses.
Flash GrenadeBlinds enemies; breaks licker hearing temporarily.Essential against Mr. X (stuns him for a few seconds).
KnifeMelee; can be thrown? Only used for slashing.Breaks after 7-8 hits on zombies. Used to escape grabs? Yes, from lickers or enemies.
Handgun Ammo9mm rounds.Combine with gunpowder for more.
Shotgun ShellsAmmo for W-870.
Grenade RoundsAmmo for GM79.
Submachine Gun AmmoNot in base RE2 remake – only in “Ghost Survivors” DLC.
High Voltage CartridgesFor Sparkshot.Rare – only 6 total per playthrough.
FuelFor Flamethrower.Found in red canisters in sewers and lab.
Magnum RoundsFor Lightning Hawk.Very rare – about 18 total if you collect all.
Regular GrenadesSame as hand grenade.
Air SprayNot an item; first aid spray.
Herb Mixing:

  • Green + Green = Medium heal (restores half health from Caution).

  • Green + Red = Full heal (from Danger to Fine).

  • Green + Blue = Heal + poison cure.

  • Green + Red + Blue = Full heal + poison cure + defense boost (temporarily reduces damage).

  • Blue + Blue = Defense boost only (no heal).


Synergy: Always carry at least one herb mix. Save First Aid Sprays for emergencies or boss fights. Use flash grenades on Mr. X to escape or during combat.

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Key Items (Plot & Puzzle Necessary)



These items cannot be discarded and are essential for progression.

ItemFunctionAcquisition
Spark Key (Leon) / Skeleton Key (Claire)Unlocks certain doors in RPD (marked with red/blue diamonds).Leon: From the jack puzzle in the shower room; Claire: From the safe in the S.T.A.R.S. office or other puzzle? Actually both get a key from the parking garage or later.
Club KeyOpens green-symbol doors.Both: From the RPD safe in the east office (9-15-7) or after the main hall puzzle?
Heart KeyOpens heart-symbol doors.Both: From the sewer control room after solving the water puzzle.
Iconic Key (Leon) / Red Jewel Key (Claire)Opens the darkroom lockers.Leon: In the parking garage office; Claire: In the S.T.A.R.S. office.
Circuit BoardFor the underground tram – powers the train.Sewers: From the generator room after pushing the crate.
T-Virus VaccineUsed to cure the infected (Sherry).Lab – from the freezer.
Film Roll (3 types)Develops photos for locker codes.Found in various desks and hidden compartments.
Portable SafeContains a weapon part or ammo; needs to be opened.East office (RPD) – combination from a memo.
Electronic Gadget (Sherry’s piece)Combines with other gadgets to make the vaccine? Actually different.Sherry part – found in the orphanage.
Gears (small/large)Repair the crane in the sewers to lower the bridge.
BatteryFor the gate in the parking garage.Found in the boiler room.
Spade Key – not used? In original.
S.T.A.R.S. BadgeOpens the S.T.A.R.S. office in RPD.
Key Card (Level 1/2/3)Lab doors.
USB DongleUnlocks weapon locker in parking garage?
Tips: Keys are single-use once unlocked? No, they stay in inventory. Use combination notes to open safes. Film rolls must be developed in the Dark Room (RPD) to reveal codes.

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Armor & Defensive Items



ItemEffectAcquisition
Body Armor (Riot Gear)Reduces damage from attacks; breaks after absorbing a few hits.Claire: Found in the S.T.A.R.S. office; Leon: In the kennel area.
Hip PouchIncreases inventory space by +2 slots.Multiple: RPD Main Hall (statue base), East Office (after breaking pot?), Parking Garage (in a crate), Sewers (near the chess puzzle), Lab (freezer).
Defense Magazine (not in base game)Not present in RE2 remake; only in RE3.
Blue Herb (preemptive)If consumed before combat, provides temporary defense boost (requires blue+blue or green+blue combo).
Synergy: Wear body armor for boss fights like G or Mr. X. Hip pouches are critical; prioritize picking them up early.

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Collectibles & Currencies



ItemUseNotes
Mr. Raccoon15 collectible figurines. Destroy all for infinite knife.Hidden in RPD, sewers, lab. Use knife or shoot.
Zombie Photographs (Sheldon’s files)No direct use – backstory.Found scattered.
DocumentsLore, puzzles.
Safe Combination NotesUnlock various safes.
Lockpick (optional)Opens simple padlocks.Found in a drawer. Can be used to skip some puzzles.
Bolt CuttersCut chain locks.Required to open certain doors.
Crank WheelTurn gear mechanisms.
Diamond Key (need use)Opens container in parking garage.
CoinsNot a currency in RE2; there are pocket coins that increase defense/attack as part of the Deluxe Edition or DLC.
Bonus Items (Shop)Unlockable infinite ammo weapons, costumes. Buy with points from challenges.
Raccoon TokensNot in RE2 remake – are from RE3.
Currencies: No traditional currency. Points earned from completing challenges (Records) can be used in the Extra Content Shop for infinite weapons, costumes, and model viewer.

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Materials (Crafting)



Crafting in RE2 involves mixing herbs and combining gunpowder to create ammo.

MaterialCreates
Gunpowder (Large)Combine with small gunpowder to create high capacity rounds? Actually gunpowder comes in small and large. Small + Small = Handgun ammo; Small + Large = Shotgun shells; Large + Large = Magnum rounds.
Gunpowder (Small)See above.
Herbs (Green, Red, Blue)See herb mixing table above.
Fuel CanistersRefill flamethrower.
High Voltage CartridgeAlready usable – no crafting.
Tip: Save large gunpowder for magnum ammo if you have the weapon. Always combine herbs for maximum efficiency.

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Special & DLC Items



ItemAcquisitionEffect
Infinite KnifeDestroy all 15 Mr. Raccoons.Unbreakable knife in new game plus.
Infinite Rocket LauncherComplete Hardcore mode with S+ rank (Scenario A).One-shot kill on any enemy.
Infinite Ammo (Handgun or Shotgun)Purchase from the Extra Content Shop with points.
Costumes: Noir, Vintage, etc.Bonus content.Cosmetic only.
Hip Pouch (extra)Included in Deluxe Edition.Extra inventory at start.
Pocket Coins (Defense/Attack)Part of Deluxe Edition.Increase damage dealt or reduce damage taken. Equip in inventory.
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Inventory Management & Synergies



  • Always keep at least one defense item: flash grenade or knife to escape grabs.

  • Prioritize hip pouches to expand slots.

  • Combine gunpowder based on current enemy density: shotguns for corridors, magnums for bosses.

  • Herb combos: Green+Red for full heal; Green+Green for mid-heal; Green+Blue for poison areas (lab).

  • Use body armor during boss encounters where you know you’ll take hits.

  • Store key items in item box when not needed; never discard them (can’t anyway).


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    Frequently Missed Items



  • Red Herbs: In sewer reachable only after lowering water; also in lab B4.

  • Body Armor (Riot Gear): In S.T.A.R.S. office for Claire, or in kennel for Leon (behind bust).

  • Hip Pouch #1: In main hall immediately after the zombie cutscene – behind the lion statue.

  • Hip Pouch #2: East office after using the green herb puzzle? Actually you need to break the glass case.

  • Mr. Raccoon #15: On the lab’s generator – shoot it before escaping.

  • Flamethrower Fuel: Two canisters in the sewer’s safe room; one in nest.


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This guide covers all items in Resident Evil 2 (2019). Use wisely, conserve ammo, and always have a backup plan. Good luck surviving Raccoon City.